2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid
platycodigenin
CAS: 22327-82-8
Molecular Formula: C30H48O7
2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid - Names and Identifiers
2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid - Physico-chemical Properties
| Molecular Formula | C30H48O7 |
| Molar Mass | 520.7 |
| Density | 1.28±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 242-243℃ |
| Boling Point | 675.5°C at 760 mmHg |
| Specific Rotation(α) | (Py)+35.3 |
| Solubility | Insuluble (6.8E-3 g/L) (25 °C) |
| Appearance | White crystal or powder |
| Storage Condition | 2-8℃ |
| MDL | MFCD21333509 |
2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid - Reference
| Reference Show more | 1. Zhang, Chi, et al. "Components study on antitussive effect and holistic mechanism of Platycodonis Radix based on spectrum-effect relationship and metabonomics analysis." Journal of Chromatography B 1173 (2021): 122680.https://doi.org/10.1016/j.jchromb.2021 2. [IF=4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447 3. [IF=3.205] Chi Zhang et al."Components study on antitussive effect and holistic mechanism of Platycodonis Radix based on spectrum-effect relationship and metabonomics analysis."J Chromatogr B. 2021 May;1173:122680 4. [IF=3.205] Chi Zhang et al."Active microbial metabolites study on antitussive and expectorant effects and metabolic mechanisms of platycosides fraction of Platycodonis Radix."J Chromatogr B. 2022 Apr;1195:123171 |
2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid - Reference Information
| Overview | platycodin is a typical two sugar chain saponin, water soluble, not easy to separate. Platycodin mainly includes two kinds of sapogenin, one is Platycodigenin, and the other is polygalacic acid. At present, most of the isolated saponins belong to these two sapogenins, including platycodin D, platycodin E, platycodin D3, Polygala saponin D, etc. |
| Use | platycodin is used as a drug or health product and food additive for the treatment of hyperlipidemia and hyperglycemia, it has the advantages of obvious curative effect and less toxic and side effects. |
| biological activity | Platicodigenin was isolated from Platycodon grandiflorum. |
Last Update：2024-04-09 19:05:15
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